Rajkumar AP, Poonkuzhali B, Kuruvilla A, Srivastava A, Jacob M, Jacob KS. Outcome definitions and clinical predictors influence pharmacogenetic associations between HTR3A gene polymorphisms and response to clozapine in patients with schizophrenia. Psychopharmacology (Berl). 2012 Dec;224(3):441-9. doi: 10.1007/s00213-012-2773-2. Epub 2012 Jun 15. PMID: 22700043.

Rajkumar AP, Poonkuzhali B, Kuruvilla A, Srivastava A, Jacob M, Jacob KS. Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. Acta Neuropsychiatr. 2013 Feb;25(1):2-11. doi: 10.1111/j.1601-5215.2012.00638.x. PMID: 26953068. Link

Rajkumar AP, Poonkuzhali B, Kuruvilla A, Jacob M, Jacob KS. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. Int Clin Psychopharmacol. 2013 Jan;28(1):50-6. doi: 10.1097/YIC.0b013e32835ac9da. PMID: 23104241.

Rajagopal V, Sundaresan L, Rajkumar AP, Chittybabu C, Kuruvilla A, Srivastava A, Balasubramanian P, Jacob KS, Jacob M. Genetic association between the DRD4 promoter polymorphism and clozapine-induced sialorrhea. Psychiatr Genet. 2014 Dec;24(6):273-6. doi: 10.1097/YPG.0000000000000058. PMID: 25304228.

Alex AA, Ganesan S, Palani HK, Balasundaram N, David S, Lakshmi KM, Kulkarni UP, Nisham PN, Korula A, Devasia AJ, Janet NB, Abraham A, Srivastava A, George B, Padua RA, Chomienne C, Balasubramanian P, Mathews V. Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis. Front Immunol. 2018 Jun 14;9:1357. doi: 10.3389/fimmu.2018.01357. PMID: 29963052; PMCID: PMC6010577.

Maddali M, Balasubramanian P. Applications of Next Generation Sequencing in Haematological Disorders-Indian Status: Updates from ISHBT 2018. Indian J Hematol Blood Transfus. 2019 Jan;35(1):17-21. doi: 10.1007/s12288-018-01068-4. Epub 2019 Jan 17. PMID: 30828142; PMCID: PMC6369091. Link

Rajkumar AP, Poonkuzhali B, Kuruvilla A, Srivastava A, Jacob M, Jacob KS. Outcome definitions and clinical predictors influence pharmacogenetic associations between HTR3A gene polymorphisms and response to clozapine in patients with schizophrenia. Psychopharmacology (Berl). 2012 Dec;224(3):441-9. doi: 10.1007/s00213-012-2773-2. Epub 2012 Jun 15. PMID: 22700043.

Rajkumar AP, Poonkuzhali B, Kuruvilla A, Srivastava A, Jacob M, Jacob KS. Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia. Acta Neuropsychiatr. 2013 Feb;25(1):2-11. doi: 10.1111/j.1601-5215.2012.00638.x. PMID: 26953068. Link

Rajkumar AP, Poonkuzhali B, Kuruvilla A, Jacob M, Jacob KS. Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia. Int Clin Psychopharmacol. 2013 Jan;28(1):50-6. doi: 10.1097/YIC.0b013e32835ac9da. PMID: 23104241.

Rajagopal V, Sundaresan L, Rajkumar AP, Chittybabu C, Kuruvilla A, Srivastava A, Balasubramanian P, Jacob KS, Jacob M. Genetic association between the DRD4 promoter polymorphism and clozapine-induced sialorrhea. Psychiatr Genet. 2014 Dec;24(6):273-6. doi: 10.1097/YPG.0000000000000058. PMID: 25304228.

Alex AA, Ganesan S, Palani HK, Balasundaram N, David S, Lakshmi KM, Kulkarni UP, Nisham PN, Korula A, Devasia AJ, Janet NB, Abraham A, Srivastava A, George B, Padua RA, Chomienne C, Balasubramanian P, Mathews V. Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis. Front Immunol. 2018 Jun 14;9:1357. doi: 10.3389/fimmu.2018.01357. PMID: 29963052; PMCID: PMC6010577.

Maddali M, Balasubramanian P. Applications of Next Generation Sequencing in Haematological Disorders-Indian Status: Updates from ISHBT 2018. Indian J Hematol Blood Transfus. 2019 Jan;35(1):17-21. doi: 10.1007/s12288-018-01068-4. Epub 2019 Jan 17. PMID: 30828142; PMCID: PMC6369091. Link

Arunachalam AK, Suresh H, Edison ES, Korula A, Aboobacker FN, George B, Shaji RV, Mathews V, Balasubramanian P. Screening of genetic variants in ELANE mutation negative congenital neutropenia by next generation sequencing. J Clin Pathol. 2020 Jun;73(6):322-327. doi: 10.1136/jclinpath-2019-206306. Epub 2019 Nov 15. PMID: 31732620. Link

Balakrishnan, Balaji, Mohanan, Ezhilpavai, Illangeswaran, Raveen Stephen Stallon, Srivastava, Alok, Mathews, Vikram and Balasubramanian, Poonkuzhali Differential Toxicity Profile of Busulfan and Treosulfan on Endothelial Cells in Vitro-Relevance to Hematopoietic Stem Cell Transplantation Biology of Blood and Marrow Transplantation; 2018, 24 (3): S313-S314

Mohanan E, Panetta JC, Lakshmi KM, Edison ES, Korula A, Fouzia NA, Abraham A, Viswabandya A, Mathews V, George B, Srivastava A, Balasubramanian P. Population pharmacokinetics of fludarabine in patients with aplastic anemia and Fanconi anemia undergoing allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2017 Jul;52(7):977-983. doi: 10.1038/bmt.2017.79. Epub 2017 May 8. Erratum in: Bone Marrow Transplant. 2018 Nov;53(11):1490. PMID: 28481355; PMCID: PMC5584518. Link

Arun AK, Senthamizhselvi A, Mani S, Vinodhini K, Janet NB, Lakshmi KM, Abraham A, George B, Srivastava A, Srivastava VM, Mathews V, Balasubramanian P. Frequency of rare BCR-ABL1 fusion transcripts in chronic myeloid leukemia patients. Int J Lab Hematol. 2017 Jun;39(3):235-242. doi: 10.1111/ijlh.12616. Epub 2016 Dec 29. PMID: 28035733. Link

Deshpande PA, Srivastava VM, Mani S, Anandhan S, Meena J, Abraham A, Viswabandya A, George B, Srivastava A, Mathews V, Balasubramanian P. Atypical BCR-ABL1 fusion transcripts in adult B-acute lymphoblastic leukemia, including a novel fusion transcript-e8a1. Leuk Lymphoma. 2016 Oct;57(10):2481-4. doi: 10.3109/10428194.2016.1151512. Epub 2016 Mar 4. PMID: 26942999. Link

Varatharajan S, Abraham A, Karathedath S, Ganesan S, Lakshmi KM, Arthur N, Srivastava VM, George B, Srivastava A, Mathews V, Balasubramanian P. ATP-binding casette transporter expression in acute myeloid leukemia: association with in vitro cytotoxicity and prognostic markers. Pharmacogenomics. 2017 Feb;18(3):235-244. doi: 10.2217/pgs-2016-0150. Epub 2017 Jan 23. PMID: 28112576. Link

Ganesan S, Alex AA, Chendamarai E, Balasundaram N, Palani HK, David S, Kulkarni U, Aiyaz M, Mugasimangalam R, Korula A, Abraham A, Srivastava A, Padua RA, Chomienne C, George B, Balasubramanian P, Mathews V. Rationale and efficacy of proteasome inhibitor combined with arsenic trioxide in the treatment of acute promyelocytic leukemia. Leukemia. 2016 Nov;30(11):2169-2178. doi: 10.1038/leu.2016.227. Epub 2016 Aug 18. PMID: 27560113; PMCID: PMC5097069. Link

Varatharajan S, Panetta JC, Abraham A, Karathedath S, Mohanan E, Lakshmi KM, Arthur N, Srivastava VM, Nemani S, George B, Srivastava A, Mathews V, Balasubramanian P. Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia. Cancer Chemother Pharmacol. 2016 Nov;78(5):1051-1058. doi: 10.1007/s00280-016-3166-8. Epub 2016 Oct 13. PMID: 27738808; PMCID: PMC7115946. Link

Abraham A, Varatharajan S, Karathedath S, Philip C, Lakshmi KM, Jayavelu AK, Mohanan E, Janet NB, Srivastava VM, Shaji RV, Zhang W, Abraham A, Viswabandya A, George B, Chandy M, Srivastava A, Mathews V, Balasubramanian P. RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia. Pharmacogenomics. 2015 Jul;16(8):877-90. doi: 10.2217/pgs.15.44. Epub 2015 Jun 17. PMID: 26083014; PMCID: PMC7115907. Link

Desire S, Mohanan EP, George B, Mathews V, Chandy M, Srivastava A, Balasubramanian P. A rapid & sensitive liquid chromatography- tandem mass spectrometry method for the quantitation of busulfan levels in plasma & application for routine therapeutic monitoring in haematopoietic stem cell transplantation. Indian J Med Res. 2013 Apr;137(4):777-84. PMID: 23703347; PMCID: PMC3724260. Link

Varatharajan S, Abraham A, Zhang W, Shaji RV, Ahmed R, Abraham A, George B, Srivastava A, Chandy M, Mathews V, Balasubramanian P. Carbonyl reductase 1 expression influences daunorubicin metabolism in acute myeloid leukemia. Eur J Clin Pharmacol. 2012 Dec;68(12):1577-86. doi: 10.1007/s00228-012-1291-9. Epub 2012 May 5. PMID: 22562609. Link

Balasubramanian P, Chendamarai E, Markose P, Fletcher L, Branford S, George B, Mathews V, Chandy M, Srivastava A. International reporting scale of BCR-ABL1 fusion transcript in chronic myeloid leukemia: first report from India. Acta Haematol. 2012;127(3):135-42. doi: 10.1159/000334716. Epub 2012 Jan 12. PMID: 22249155. Link

Balasubramanian P, Desire S, Panetta JC, Lakshmi KM, Mathews V, George B, Viswabandya A, Chandy M, Krishnamoorthy R, Srivastava A. Population pharmacokinetics of cyclophosphamide in patients with thalassemia major undergoing HSCT. Bone Marrow Transplant. 2012 Sep;47(9):1178-85. doi: 10.1038/bmt.2011.254. Epub 2012 Jan 9. PMID: 22231460. Link

Arora N, Nair S, Pai R, Nair S, Ahmed R, Abraham A, Viswabandya A, George B, Balasubramanian P, Srivastava A, Mathews V. V-raf murine sarcoma viral oncogene homolog B (BRAF) mutations in hairy cell leukaemia. Indian J Pathol Microbiol. 2015 Jan-Mar;58(1):62-5. doi: 10.4103/0377-4929.151190. PMID: 25673595. Link

Abraham A, Karathedath S, Kumaraswamy V, Jayavelu AK, Mani S, Srivastava VM, Zhang W, Zhou T, George B, Srivastava A, Mathews V, Balasubramanian P. Novel NPM1 mutation in the 3'-untranslated region identified in two patients with acute myeloid leukemia. Leuk Lymphoma. 2014 Jun;55(6):1421-4. doi: 10.3109/10428194.2013.838235. Epub 2013 Oct 9. PMID: 23998253. Link

Chendamarai E, Balasubramanian P, George B, Viswabandya A, Abraham A, Ahmed R, Alex AA, Ganesan S, Lakshmi KM, Sitaram U, Nair SC, Chandy M, Janet NB, Srivastava VM, Srivastava A, Mathews V. Role of minimal residual disease monitoring in acute promyelocytic leukemia treated with arsenic trioxide in frontline therapy. Blood. 2012 Apr 12;119(15):3413-9. doi: 10.1182/blood-2011-11-393264. Epub 2012 Feb 28. PMID: 22374701. Link

Desire S, Balasubramanian P, Bajel A, George B, Viswabandya A, Mathews V, Srivastava A, Chandy M. Frequency of TPMT alleles in Indian patients with acute lymphatic leukemia and effect on the dose of 6-mercaptopurine. Med Oncol. 2010 Dec;27(4):1046-9. doi: 10.1007/s12032-009-9331-8. Epub 2009 Oct 15. PMID: 19830600. Link

Devasia, Anup, Korula, Anu, Kulkarni, Uday, Fouzia, N. A., Abraham, Aby, Srivastava, Alok, George, Biju, Balasubramaniam, Poonkuzhali and Mathews, Vikram Hairy Cell Leukemia: Long Term Response to Cladribine Clinical Lymphoma Myeloma & Leukemia; 2018, 18 S280-S280 Link

Parihar M, Kumar JA, Sitaram U, Balasubramanian P, Abraham A, Viswabandya A, George B, Mathews V, Srivastava A, Srivastava VM. Cytogenetic analysis of acute myeloid leukemia with t(8;21) from a tertiary care center in India with correlation between clinicopathologic characteristics and molecular analysis. Leuk Lymphoma. 2012 Jan;53(1):103-9. doi: 10.3109/10428194.2011.603447. Epub 2011 Sep 2. PMID: 21745004. Link

Gupta M, Ashok Kumar J, Sitaram U, Neeraj S, Nancy A, Balasubramanian P, Abraham A, Mathews V, Viswabandya A, George B, Chandy M, Srivastava A, Srivastava VM. The t(6;9)(p22;q34) in myeloid neoplasms: a retrospective study of 16 cases. Cancer Genet Cytogenet. 2010 Dec;203(2):297-302. doi: 10.1016/j.cancergencyto.2010.08.012. PMID: 21156248. Link

Mathews V, George B, Chendamarai E, Lakshmi KM, Desire S, Balasubramanian P, Viswabandya A, Thirugnanam R, Abraham A, Shaji RV, Srivastava A, Chandy M. Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: long-term follow-up data. J Clin Oncol. 2010 Aug 20;28(24):3866-71. doi: 10.1200/JCO.2010.28.5031. Epub 2010 Jul 19. PMID: 20644086. Link

Thirugnanam R, George B, Chendamarai E, Lakshmi KM, Balasubramanian P, Viswabandya A, Srivastava A, Chandy M, Mathews V. Comparison of clinical outcomes of patients with relapsed acute promyelocytic leukemia induced with arsenic trioxide and consolidated with either an autologous stem cell transplant or an arsenic trioxide-based regimen. Biol Blood Marrow Transplant. 2009 Nov;15(11):1479-84. doi: 10.1016/j.bbmt.2009.07.010. Epub 2009 Sep 1. PMID: 19822309. Link

Jain P, Korula A, Deshpande P, Pn N, Abu Alex A, Abraham A, Srivastava A, Janet NB, Lakshmi KM, Balasubramanian P, George B, Mathews V. Adult Acute Lymphoblastic Leukemia: Limitations of Intensification of Therapy in a Developing Country. J Glob Oncol. 2018 Sep;4:1-12. doi: 10.1200/JGO.17.00014. PMID: 30222028; PMCID: PMC6371642.

Pai AA, Devasia AJ, Panetta JC, Mani S, Stallon Illangeswaran RS, Mohanan E, Balakrishnan B, Lakshmi KM, Kulkarni U, Aboobacker FN, Korula A, Abraham A, Srivastava A, Mathews V, George B, Balasubramanian P. Pharmacokinetics and Efficacy of Generic Melphalan Is Comparable to Innovator Formulation in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplantation. Clin Lymphoma Myeloma Leuk. 2020 Feb;20(2):130-135.e1. doi: 10.1016/j.clml.2019.08.013. Epub 2019 Oct 4. PMID: 31791694; PMCID: PMC7115908.

Pai, Aswin Anand, Mohanan, Ezhilpavai, Balakrishnan, Balaji, Amirthavani, G., Illangeswaran, Raveen Stephen Stallon, Panetta, John Carl, George, Biju, Mathews, Vikram, Srivastava, Alok and Balasubramanian, Poonkuzhali Genetic Variants in Drug Metabolizing and Transporter Genes Explain Variability in Fludarabine Pharmacokinetics in Patients Undergoing HSCT Biology of Blood and Marrow Transplantation; 2018, 24 (3): S53-S53 Link

Chandy M, Balasubramanian P, Ramachandran SV, Mathews V, George B, Dennison D, Krishnamoorthy R, Srivastava A. Randomized trial of two different conditioning regimens for bone marrow transplantation in thalassemia--the role of busulfan pharmacokinetics in determining outcome. Bone Marrow Transplant. 2005 Nov;36(10):839-45. doi: 10.1038/sj.bmt.1705151. PMID: 16151422. Link

Mathews V, Balasubramanian P, Shaji RV, George B, Chandy M, Srivastava A. Arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: a single center experience. Am J Hematol. 2002 Aug;70(4):292-9. doi: 10.1002/ajh.10138. PMID: 12210810. Link

George B, Poonkuzhali B, Srivastava VM, Chandy M, Srivastava A. Hematological and molecular remission with combination chemotherapy in a patient with PLZF-RARalpha acute promyelocytic leukemia (APML). Ann Hematol. 2005 Jun;84(6):406-8. doi: 10.1007/s00277-004-0979-z. Epub 2004 Dec 7. PMID: 15592671. Link

George B, Mathews V, Poonkuzhali B, Shaji RV, Srivastava A, Chandy M. Treatment of children with newly diagnosed acute promyelocytic leukemia with arsenic trioxide: a single center experience. Leukemia. 2004 Oct;18(10):1587-90. doi: 10.1038/sj.leu.2403480. PMID: 15356649. Link

Srivastava A, Poonkuzhali B, Shaji RV, George B, Mathews V, Chandy M, Krishnamoorthy R. Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation. Blood. 2004 Sep 1;104(5):1574-7. doi: 10.1182/blood-2003-11-3778. Epub 2004 May 13. PMID: 15142875. Link

Fouzia NA, Sharma V, Ganesan S, Palani HK, Balasundaram N, David S, Kulkarni UP, Korula A, Devasia AJ, Nair SC, Janet NB, Abraham A, Mani T, Lakshmanan J, Balasubramanian P, George B, Mathews V. Management of relapse in acute promyelocytic leukaemia treated with up-front arsenic trioxide-based regimens. Br J Haematol. 2021 Jan;192(2):292-299. doi: 10.1111/bjh.17221. Epub 2020 Nov 20. PMID: 33216980; PMCID: PMC7894296.

Janet NB, Kulkarni U, Arun AK, Bensega B, Devasia AJ, Korula A, Abraham A, George B, Mathews V, Balasubramanian P. Systematic application of fluorescence in situ hybridization and immunophenotype profile for the identification of ZNF384 gene rearrangements in B cell acute lymphoblastic leukemia. Int J Lab Hematol. 2021 May 14. doi: 10.1111/ijlh.13580. Epub ahead of print. PMID: 33988307.

Mathews V, George B, Lakshmi KM, Viswabandya A, Bajel A, Balasubramanian P, Shaji RV, Srivastava VM, Srivastava A, Chandy M. Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity. Blood. 2006 Apr 1;107(7):2627-32. doi: 10.1182/blood-2005-08-3532. Epub 2005 Dec 13. PMID: 16352810.

Ezhilarasi Chendamarai, MSc, Poonkuzhali Balasubramanian, PhD, Kavitha Lakshmi, MSc, Auro Viswabandya, MD, Biju George, MD, Alok Srivastava, MD, Mammen Chandy, MD, Vikram Mathews, MD Minimal Residual Disease Monitoring in Patients with Newly Diagnosed Acute Promyelocytic Leukemia Treated with Arsenic Trioxide Blood (2008) 112 (11): 2534. Link

Abraham A, Devasia AJ, Varatharajan S, Karathedath S, Balasubramanian P, Mathews V. Effect of cytosine arabinoside metabolizing enzyme expression on drug toxicity in acute myeloid leukemia. Ann Hematol. 2015 May;94(5):883-5. doi: 10.1007/s00277-014-2254-2. Epub 2014 Nov 13. PMID: 25391240; PMCID: PMC5681861. Link

Mathews V, Balasubramanian P, Shaji RV, George B, Chandy M, Srivastava A. Central nervous system relapse in a patient with acute promyelocytic leukaemia treated with arsenic tri-oxide. Br J Haematol. 2001 Apr;113(1):257-8. doi: 10.1046/j.1365-2141.2001.02673-4.x. PMID: 11360894. Link

Mohanan E, Panetta JC, Lakshmi KM, Edison ES, Korula A, Na F, Abraham A, Viswabandya A, George B, Mathews V, Srivastava A, Balasubramanian P. Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Clin Pharmacol Ther. 2018 Sep;104(3):575-583. doi: 10.1002/cpt.988. Epub 2018 Jan 17. PMID: 29247522; PMCID: PMC6045930. Link

Fouzia NA, Edison ES, Lakshmi KM, Korula A, Velayudhan SR, Balasubramanian P, Abraham A, Viswabandya A, George B, Mathews V, Srivastava A. Long-term outcome of mixed chimerism after stem cell transplantation for thalassemia major conditioned with busulfan and cyclophosphamide. Bone Marrow Transplant. 2018 Feb;53(2):169-174. doi: 10.1038/bmt.2017.231. Epub 2017 Oct 16. PMID: 29035392. Link

Ganapule A, Nemani S, Korula A, Lakshmi KM, Abraham A, Srivastava A, Balasubramanian P, George B, Mathews V. Allogeneic Stem Cell Transplant for Acute Myeloid Leukemia: Evolution of an Effective Strategy in India. J Glob Oncol. 2017 Dec;3(6):773-781. doi: 10.1200/JGO.2016.006650. Epub 2017 Feb 8. PMID: 24498329; PMCID: PMC5735966. Link

Angi M, Kamath V, Yuvarani S, Meena J, Sitaram U, Manipadam MT, Nair S, Ganapule A, Fouzia NA, Abraham A, Viswabandya A, Poonkuzhali B, George B, Mathews V, Srivastava A, Srivastava VM. The t(8;14)(q24.1;q32) and its variant translocations: A study of 34 cases. Hematol Oncol Stem Cell Ther. 2017 Sep;10(3):126-134. doi: 10.1016/j.hemonc.2017.03.002. Epub 2017 Mar 31. PMID: 28390216. Link

Philip C, George B, Korula A, Srivastava A, Balasubramanian P, Mathews V. Treatment rates of paediatric acute myeloid leukaemia: a view from three tertiary centres in India - response to Gupta et al. Br J Haematol. 2016 Oct;175(2):347-349. doi: 10.1111/bjh.13857. Epub 2015 Dec 2. PMID: 26627639. Link

Philip C, George B, Ganapule A, Korula A, Jain P, Alex AA, Lakshmi KM, Sitaram U, Abubacker FN, Abraham A, Viswabandya A, Srivastava VM, Srivastava A, Balasubramanian P, Mathews V. Acute myeloid leukaemia: challenges and real world data from India. Br J Haematol. 2015 Jul;170(1):110-7. doi: 10.1111/bjh.13406. Epub 2015 Apr 9. PMID: 25858293; PMCID: PMC4864448. Link

Chendamarai E, Ganesan S, Alex AA, Kamath V, Nair SC, Nellickal AJ, Janet NB, Srivastava V, Lakshmi KM, Viswabandya A, Abraham A, Aiyaz M, Mullapudi N, Mugasimangalam R, Padua RA, Chomienne C, Chandy M, Srivastava A, George B, Balasubramanian P, Mathews V. Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance. PLoS One. 2015 Mar 30;10(3):e0121912. doi: 10.1371/journal.pone.0121912. PMID: 25822503; PMCID: PMC4378855. Link

Abraham A, Karathedath S, Varatharajan S, Markose P, Chendamarai E, Jayavelu AK, George B, Srivastava A, Mathews V, Balasubramanian P. ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia. Ann Hematol. 2014 Mar;93(3):509-12. doi: 10.1007/s00277-013-1821-2. Epub 2013 Jun 22. PMID: 23793916. Link

Agarwala MK, George R, Mathews V, Balasubramanian P, Thomas M, Nair S. Role of imatinib in the treatment of pediatric onset indolent systemic mastocytosis: a case report. J Dermatolog Treat. 2013 Dec;24(6):481-3. doi: 10.3109/09546634.2013.802274. Epub 2013 May 30. PMID: 23659595.

Pai AA, Mohan A, Benjamin ESB, Illangeswaran RSS, Xavier Raj I, Janet NB, Arunachalam AK, Kavitha ML, Kulkarni U, Devasia AJ, Fouzia NA, Abraham A, Srivastava A, George B, Mathews V, Korula A, Balasubramanian P. NUDT15 c.415C>T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy. Pharmgenomics Pers Med. 2021 Oct 2;14:1303-1313. doi: 10.2147/PGPM.S325813. PMID: 34629890; PMCID: PMC8495143.

Karathedath S, Rajamani BM, Musheer Aalam SM, Abraham A, Varatharajan S, Krishnamurthy P, Mathews V, Velayudhan SR, Balasubramanian P. Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2. PLoS One. 2017 May 15;12(5):e0177227. doi: 10.1371/journal.pone.0177227. PMID: 28505160; PMCID: PMC5432104.

Kulkarni UP, Pai AA, Kavitha ML, Selvarajan S, Lionel S, Devasia AJ, Korula A, Fouzia NA, Sindhuvi E, Abraham A, Srivastava A, Mathews V, George B, Balasubramanian P. Endothelial Activation and Stress Index-Measured Pretransplantation Predicts Transplantation-Related Mortality in Patients with Thalassemia Major Undergoing Transplantation with Thiotepa, Treosulfan, and Fludarabine Conditioning. Transplant Cell Ther. 2022 Jul;28(7):356.e1-356.e6. doi: 10.1016/j.jtct.2022.05.001. Epub 2022 May 9. PMID: 35550442.

Kulkarni UP, Selvarajan S, Lionel S, Prakash MA, Palani HK, Balasundaram N, Venkataraman A, Korula A, Devasia AJ, Fouzia NA, Janet NB, Nair SC, Abraham A, Mani T, Lakshmanan J, Arunachalam AK, Balasubramanian P, George B, Mathews V. Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia. Blood Cancer J. 2022 Jan 31;12(1):22. doi: 10.1038/s41408-022-00619-3. PMID: 35102152; PMCID: PMC8803919. Link

Roy S, Manipadam MT, Balasubramanian P. Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation. Turk Patoloji Derg. 2022;38(1):25-33. English. doi: 10.5146/tjpath.2021.01550. PMID: 34514582.

Balasundaram N, Ganesan S, Chendamarai E, Palani HK, Venkatraman A, Alex AA, David S, Kumar SP, Radhakrishnan NR, Yasar M, Krishna S, Korula A, Kulkarni U, Janet NB, Balasubramanian P, Mathews V. Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia. Blood Adv. 2022 Jan 25;6(2):652-663. doi: 10.1182/bloodadvances.2021005300. PMID: 34625794; PMCID: PMC8791572.

Jain P, Deshpande P, Korula A, Nisham P N, Alex AA, Fouzia NA, Lakshmi K, Abraham A, Balasubramanian P, Srivastava A, George B, Mathews V. Adult Acute Lymphoblastic Leukemia: A Cost Effective Strategy and Limitations of Intensification of Therapy in India. Blood (2015) 126 (23): 3732.

Sathishkumar D, Balasundaram A, Mathew SM, Mathew L, Thomas M, Balasubramanian P, George R. Clinicopathological Profile of Childhood Onset Cutaneous Mastocytosis from a Tertiary Care Center in South India. Indian Dermatol Online J. 2021 Sep 10;12(5):706-713. doi: 10.4103/idoj.IDOJ_924_20. PMID: 34667757; PMCID: PMC8456265.

Maddali M, Kulkarni UP, Ravindra N, Jajodia E, Arunachalam AK, Suresh H, Venkatraman A, George B, Mathews V, Balasubramanian P. JAK2 exon 12 mutations in cases with JAK2V617F-negative polycythemia vera and primary myelofibrosis. Ann Hematol. 2020 May;99(5):983-989. doi: 10.1007/s00277-020-04004-7. Epub 2020 Apr 10. PMID: 32277273; PMCID: PMC7611239.

Devasia, A. J., Pai, A. A., Prakash, M. A., Lakshmi, K. M., Korula, A., Kulkarni, U., Aboobacker, F. N., Lionel, S., Selvarajan, S., Abraham, A., Srivastava, A., Mathews, V., Balasubramanian, P. and George, B MM-134 Comparable Toxicity and Outcomes With Generic and Innovator Melphalan in Myeloma Auto Transplants. Clinical Lymphoma, Myeloma and Leukemia; 2022, 22 S407 Link

Venkatesan V, Christopher AC, Rhiel M, Azhagiri MKK, Babu P, Walavalkar K, Saravanan B, Andrieux G, Rangaraj S, Srinivasan S, Karuppusamy KV, Jacob A, Bagchi A, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Pai R, Marepally SK, Mohankumar KM, Velayudhan SR, Boerries M, Notani D, Cathomen T, Srivastava A, Thangavel S. Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies. Mol Ther Nucleic Acids. 2023 Apr 26;32:671-688. doi: 10.1016/j.omtn.2023.04.024. PMID: 37215154; PMCID: PMC10197010. Link

Balakrishnan B, Kulkarni UP, Pai AA, Illangeswaran RSS, Mohanan E, Mathews V, George B, Balasubramanian P. Biomarkers for early complications post hematopoietic cell transplantation: Insights and challenges. Front Immunol. 2023 Feb 2;14:1100306. doi: 10.3389/fimmu.2023.1100306. PMID: 36817455; PMCID: PMC9932777.

Rajamani BM, Benjamin ESB, Abraham A, Ganesan S, Lakshmi KM, Anandan S, Karathedath S, Varatharajan S, Mohanan E, Janet NB, Srivastava VM, Ramachandran Velayudhan S, Kulkarni UP, Devasia AJ, Fouzia NA, Korula A, George B, Srivastava A, Mathews V, Balasubramanian P. Plasma imatinib levels and ABCB1 polymorphism influences early molecular response and failure-free survival in newly diagnosed chronic phase CML patients. Sci Rep. 2020 Nov 26;10(1):20640. doi: 10.1038/s41598-020-77140-9. PMID: 33244077; PMCID: PMC7691501.

Maddali M, Venkatraman A, Kulkarni UP, Mani S, Raj S, Sigamani E, Korula A, A FN, Lionel SA, Selvarajan S, Manipadam MT, Abraham A, George B, Mathews V, Balasubramanian P. Molecular characterization of triple-negative myeloproliferative neoplasms by next-generation sequencing. Ann Hematol. 2022 Jul 15. doi: 10.1007/s00277-022-04920-w. Epub ahead of print. PMID: 35840818.

Maddila SC, Voshavar C, Arjunan P, Chowath RP, Rachamalla HKR, Balakrishnan B, Balasubramanian P, Banerjee R, Marepally S. Cholesterol Sequestration from Caveolae/Lipid Rafts Enhances Cationic Liposome-Mediated Nucleic Acid Delivery into Endothelial Cells. Molecules. 2021 Jul 30;26(15):4626. doi: 10.3390/molecules26154626. PMID: 34361779; PMCID: PMC8346983.

Benjamin ESB, Ravindra N, Rajamani BM, Anandan S, Kausalya B, Veldore V, Mathews V, Velayudhan SR, Balasubramanian P. BCR-ABL1 kinase domain mutation analysis by next generation sequencing detected additional mutations in chronic myeloid leukemia patients with suboptimal response to imatinib. Leuk Lymphoma. 2021 Jun;62(6):1528-1531. doi: 10.1080/10428194.2021.1872074. Epub 2021 Jan 22. PMID: 33478278; PMCID: PMC7611165.

Raveen Stephen Stallon Illangeswaran, Sreeja Karathedath, Abhirup Bagchi, Bharathi M Rajamani, Balaji Balakrishnan, Vikram Mathews, Shaji Ramachandran Velayudhan, Poonkuzhali Balasubramanian; Genetic Ablation of Nuclear Receptor Interacting Protein 1 (NRIP1) Sensitizes Acute Myeloid Leukemia Cells to Retinoic Acids. Blood 2021; 138 (Supplement 1): 1146. doi: https://doi.org/10.1182/blood-2021-152058

5 NOVEMBER 2021 | VOLUME 138, NUMBER Supplement 1

Nithya Balasundaram, Arvind Venkatraman, Yolanda Augustin, Hamenth Kumar Palani, Swathy Palanikumar, Nair Reeshma Radhakrishnan, Anu Korula, Uday Prakash Kulkarni, Poonkuzhali Balasubramanian, Eunice Sindhuvi, Biju George, Sanjeev Krishna, Vikram Mathews, Combining Arsenic Trioxide and Mitocans Selectively Disrupts Cellular Energetics in Acute Myeloid Leukemia, Blood,Volume 138, Supplement 1, 2021, Link

Uday Prakash Kulkarni, Aswin Anand Pai, Kavitha M Lakshmi, Sushil Selvarajan, Sharon Lionel, Anup J Devasia, Anu Korula, Fouzia NA, Eunice Sindhuvi, Aby Abraham, Alok Srivastava, Vikram Mathews, Biju George, Poonkuzhali Balasubramanian; Endothelial Activation and Stress Index (EASIX) Measured Pre-Transplant Identifies a Subgroup with High Transplant Related Mortality in Patients with Thalassemia Undergoing Stem Cell Transplantation Using Thiotepa-Treosulfan-Fludarabine Conditioning. Blood 2021; 138 (Supplement 1): 1781. https://doi.org/10.1182/blood-2021-152153

Bagchi A, Devaraju N, Chambayil K, Rajendiran V, Venkatesan V, Sayed N, Pai AA, Nath A, David E, Nakamura Y, Balasubramanian P, Srivastava A, Thangavel S, Mohankumar KM, Velayudhan SR. Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications. Sci Rep. 2022 Aug 18;12(1):14033. doi: 10.1038/s41598-022-13783-0. PMID: 35982069; PMCID: PMC9388678.

George A, Ravi NS, Prasad K, Panigrahi L, Koikkara S, Rajendiran V, Devaraju N, Paul J, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, Mohankumar KM. Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2. Front Genome Ed. 2022 Dec 20;4:1085111. doi: 10.3389/fgeed.2022.1085111. PMID: 36605051; PMCID: PMC9808041

David S, Kamath V, Kulkarni U, Vijayan R, Korula A, Fouzia NA, Nisham PN, Srivastava A, Lakshmi KM, Balasubramanian P, George B ,Nair SC. Coagulopathy in Acute Promyelocytic Leukemia: Strategies to Improve Assessment of Hemostatic Risk . Blood (2015) 126 (23): 3758.

Illangeswaran RSS, Jebanesan DZP, Sivakumar KK, Vidhyadharan RT, Rajamani BM, Janet NB, David E, Velayudhan SR, Mathews V, Balasubramanian P. Corrigendum to "Chemotherapeutic drugs elicit stemness and metabolic alteration to mediate acquired drug-resistant phenotype in acute myeloid leukemia cell lines" [Leukemia Res. 128, 107054]. Leuk Res. 2023 Jul;130:107329. doi: 10.1016/j.leukres.2023.107329. Epub 2023 May 29. Erratum for: Leuk Res. 2023 May;128:107054. PMID: 37258357.

Kulkarni UP, Selvarajan S, Lionel S, Prakash MA, Palani HK, Balasundaram N, Venkataraman A, Korula A, Devasia AJ, Fouzia NA, Janet NB, Nair SC, Abraham A, Mani T, Lakshmanan J, Arunachalam AK, Balasubramanian P, George B, Mathews V. Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia. Blood Cancer J. 2022 Jan 31;12(1):22. doi: 10.1038/s41408-022-00619-3. PMID: 35102152; PMCID: PMC8803919.

Roy S, Manipadam MT, Balasubramanian P. Calreticulin Immunohistochemistry in Myeloproliferative Neoplasms - Evolution of a New Cost-Effective Diagnostic Tool: A Retrospective Study with Histological and Molecular Correlation. Turk Patoloji Derg. 2022;38(1):25-33. English. doi: 10.5146/tjpath.2021.01550. PMID: 34514582.

Kulkarni UP, Selvarajan S, Fouzia NA, Lionel S, Nair SC, Balasubramanian P, Mani T, Abraham A, George B, Mathews V. Intracranial bleeding in acute promyelocytic leukemia treated with arsenic trioxide based regimens is associated with induction mortality but not with relapse. Blood Cancer J. 2023 Jun 22;13(1):94. doi: 10.1038/s41408-023-00873-z. PMID: 37349334; PMCID: PMC10287743.

A P R, C C, S B, B P, A K, K S J. Clinical Predictors of Response to Clozapine in Patients with Treatment Resistant Schizophrenia. Psychopharmacol Bull. 2011 Sep 15;44(3):51-65. PMID: 27738362; PMCID: PMC5044549. Link

Arunachalam AK, Selvarajan S, Mani T, Janet NB, Maddali M, Lionel SA, Kulkarni U, Korula A, Aboobacker FN, Abraham A, George B, Balasubramanian P, Mathews V. Clinical significance of end of induction measurable residual disease monitoring in B-cell acute lymphoblastic leukemia: A single center experience. Cytometry B Clin Cytom. 2023 Nov;104(6):440-452. doi: 10.1002/cyto.b.22139. Epub 2023 Aug 9. PMID: 37555390.

Rajendiran V, Devaraju N, Haddad M, Ravi NS, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AA, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S, Velayudhan SR, Corn JE, Mackay JP, Marepally S, Srivastava A, Crossley M, Mohankumar KM. Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression. Mol Ther. 2024 Jan 24:S1525-0016(24)00023-6. doi: 10.1016/j.ymthe.2024.01.023. Epub ahead of print. PMID: 38273654.

Balakrishnan B, Illangeswaran RSS, Rajamani BM, Arunachalam AK, Pai AA, Mohanan E, Srivastava A, Mathews V, Balasubramanian P. Metformin pretreatment ameliorates busulfan-induced liver endothelial toxicity during haematopoietic stem cell transplantation. PLoS One. 2023 Oct 26;18(10):e0293311. doi: 10.1371/journal.pone.0293311. PMID: 37883349; PMCID: PMC10602364.

Pai AA, Mohanan E, Panetta JC, Kulkarni UP, Illangeswaran RSS, Balakrishnan B, Jayaraman A, Edison ES, Lakshmi KM, Devasia AJ, Fouzia NA, Korula A, Abraham A, George B, Srivastava A, Mathews V, Standing JF, Balasubramanian P. Treosulfan Exposure Predicts Thalassemia-Free Survival in Patients with Beta Thalassemia Major Undergoing Allogeneic Hematopoietic Cell Transplantation. Clin Pharmacol Ther. 2024 Jan;115(1):116-125. doi: 10.1002/cpt.3078. Epub 2023 Nov 7. PMID: 37846495.

Antonisamy N, Boddu D, John R, Korrapolu RSA, Balasubramanian P, Arunachalam AK, Joseph LL, Srinivasan HN, Mathew LG, Totadri S. The Outcome of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Experience from a Referral Center in South India. Indian J Hematol Blood Transfus. 2024 Jan;40(1):61-67. doi: 10.1007/s12288-023-01684-9. Epub 2023 Aug 9. PMID: 38312177; PMCID: PMC10830957.

Benjamin ESB, Vinod E, Illangeswaran RSS, Rajamani BM, Vidhyadharan RT, Bagchi A, Maity A, Mohan A, Parasuraman G, Amirtham SM, Abraham A, Velayudhan SR, Balasubramanian P. Immortalised chronic myeloid leukemia (CML) derived mesenchymal stromal cells (MSCs) line retains the immunomodulatory and chemoprotective properties of CML patient-derived MSCs. Cell Signal. 2024 Jan 27;116:111067. doi: 10.1016/j.cellsig.2024.111067. Epub ahead of print. PMID: 38281615. Link

Palani HK, Ganesan S, Balasundaram N, Venkatraman A, Kulkarni U, Korula A, Nair SC, Mani T, Balasubramanian P, Abraham A, Puttamallesh VN, Gowda H, Mathews V. Cystatin F a potential diagnostic biomarker in acute promyelocytic leukemia. Ann Hematol. 2024 Mar 1. doi: 10.1007/s00277-024-05673-4. Epub ahead of print. PMID: 38427058.

Rajamani BM, Illangeswaran RSS, Benjamin ESB, Balakrishnan B, Jebanesan DZP, Das S, Pai AA, Vidhyadharan RT, Mohan A, Karathedath S, Abraham A, Mathews V, Velayudhan SR, Balasubramanian P. Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo. Front Pharmacol. 2023 May 31;14:1187066. doi: 10.3389/fphar.2023.1187066. PMID: 37324449; PMCID: PMC10264673.

Kulkarni U, Arunachalam AK, Palani HK, Nair RR, Balasundaram N, Venkatraman A, Korula A, Selvarajan S, Lionel S, Balasubramanian P, Maddali M, Abraham A, George B, Mathews V. Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia. Cell Transplant. 2023 Jan-Dec;32:9636897231198178. doi: 10.1177/09636897231198178. PMID: 37706453; PMCID: PMC10503284.

Jebanesan DZP, Illangeswaran RSS, Rajamani BM, Vidhyadharan RT, Das S, Bijukumar NK, Balakrishnan B, Mathews V, Velayudhan SR, Balasubramanian P. Inhibition of NRF2 signaling overcomes acquired resistance to arsenic trioxide in FLT3-mutated Acute Myeloid Leukemia. Ann Hematol. 2024 Jun;103(6):1919-1929. doi: 10.1007/s00277-024-05742-8. Epub 2024 Apr 17. PMID: 38630133. Link